ANTIMICROBIAL RESISTANCE OF STAPHYLOCOCCUS AUREUS AMONG HEALTHY AND ADULT STUDENTS

Background: Antimicrobial resistance against S.aureus infections is a global public health problem resulting in very limited treatment options, and inappropriate use of antibiotics is one of the most important factors that could affect the increasing pattern of resistance. Objective: To determine the antimicrobial resistance pattern of S. aureus among healthy and adult students to commonly used antimicrobial agents. Materials and Methods: This study was carried out at Cytogene Research and Development laboratory, Indira Nagar, Lucknow, India. Samples from throat were collected as throat-swab which were cultured and screened for S. aureus using standard microbiological protocols. The antimicrobial susceptibility of identified S. aureus was evaluated using disc diffusion technique. Results: A total of 47(54%) S. aureus were identified from 87growths of the 185throat swab samples. All the S. aureus isolates were methicillin resistant; they exhibited total resistance to penicillin, 100% to Erythromycin, 97.8%‏‏to Amoxicillin, 91.4% to Clindamycin, 78.7% to Vancomycin, 53.1% to Gentamicin, 44.6% to Trimethoprime, 19.1% to Tetracycline and 6.3% to Ciprofloxacin. Conclusion: The resistance to antibiotics agents is a global problem. Antimicrobial resistance has resulted. in increased morbidity and mortality as well as higher health care costs.