SESAME SEEDS: A PROMISING ANTI-DIABETIC AGENT

The day-by-day escalation of different diseases worldwide increases the demand for newer drugs with better therapeutic effects. Nature attracts researchers due to its rich herbal sources with potent effects against various diseases. Sesame seed acts as a reservoir for various bioactive components, exhibiting tremendous beneficial effects on human health. Sesame seed is not just only seeds that are consumed by the different parts of India but also plays an important into the lives of different communities, in their culture, and in the traditional system of medicine. Lignans are the major bioactive components of sesame seed reported to have many properties such as anti-diabetic, antioxidant, anticancer, and anti-inflammatory activities. Because of the oxidative coupling of β-hydroxyphenyl propane, different lignans are formed, such as Sesamin, Sisamol, Sesamolin, sesaminol. Due to the presence of multifarious bioactive components in sesame seeds, such as phenolic components, flavonoids sesame seeds bear a possibility to be an agent in controlling diabetes and hyperlipidemia by decreasing oxidative stress and inflammatory responses. This review focuses on the functional importance of lignans &in future scientific studies, clinical testing of the Sesame liganans in diabetic patients could provide plenty of opportunities and possibilities to the researchers.