¬POST-STROKE DEPRESSION: PATHOLOGLOGY, DIAGNOSIS AND TREATMENT STRATEGYAbstract
Post stroke depression is most commonly faced psychiatric challenge, causing severe disability. Post stroke depression (PSD) occurs in nearly one-third patients either during acute/chronic stroke period. It’s often under-diagnosed. A good diagnosis must be done within one month after stroke, based on self-reporting tools, followed by observer-rated interview. Mechanism is multifactorial, presently best supported by biopsychosocial model. Upcoming approaches are genetic based and cytokine theory. About 10% PSD patients face mortality. There is a huge negative biological and psychosocial impact of PSD. Currently, pharmacological and non-pharmacological way-outs are used to manage the PSD. However, precise and timely done evaluation aided by proper therapy and utmost care is also required, under the supervision of a multidisciplinary health team.
Anil Kumar*, Aditi Aggarwal and Vaibhav Gaur
Pharmacology division, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India
15 November, 2010
27 January, 2011
12 February, 2011
01 March, 2011