A REVIEW ON RECENT ADVANCES IN EMERGING NANOPARTICLE-BASED BUCCAL DELIVERY SYSTEMS FOR ANTI-RETROVIRAL DRUG DELIVERY

The development of mucoadhesive buccal formulations has recently gained a great deal of attention. Despite several proposed solutions, drug permeability and regulated drug release via this mode of delivery remain concerns for successful therapy. Clinical uses for recent advances in nanotechnology have been examined. In addition to ensuring effective distribution, the use of nanoparticles in dosage forms for buccal administration also helps to minimize any negative effects on biological systems. To load and distribute drug-containing nanoparticles to the buccal mucosa for topical and systemic applications, several strategies have been proposed. In order to improve medication delivery or targeting, this study outlines contemporary cutting-edge approaches for using nanoparticles in dosage forms. Of give a general overview of current approaches to implementing controlled drug delivery, these technologies are categorized and discussed. All of these noteworthy results will promote novel nanoparticle-delivered dose formulations for buccal distribution in clinical settings. Overall, the buccal mucosa provides a lot of advantages for controlled pharmaceutical delivery over an extended period of time.