A REVIEW ON THE APPROPRIATENESS OF SURGICAL PROPHYLAXIS IN OBSTETRICS AND GYNAECOLOGYAbstract
AIM: This review aims to analyze the appropriateness of surgical antimicrobial prophylaxis in obstetrics and gynecology from 2015 to June 2022. Methodology: The review includes interventional, prospective and retrospective observational studies and surveys based on compliance with surgical antibiotic prophylaxis use concerning standard surgical antimicrobial prophylaxis (SAP) guidelines for gynecological and obstetrics surgeries from a web search of PubMed and Google Scholar from the year of 2015 to June 2022. Results: The review describes 33 studies focused on the appropriate usage of surgical prophylactic antibiotics. The majority of the studies revealed excessive and inappropriate use, and the compliance is far below the recommended guidelines, especially in terms of duration which is followed by the selection and time of administration of antibiotics. Conclusion: The majority of the studies analyzed in this review indicated a remarkable rate of inappropriateness, which may contribute to antimicrobial resistance (AMR), which raises the risk of SSI exacerbated by resistant bacteria followed by prolonged hospitalization and increased mortality. There is evidence that pharmacist intervention promotes the optimal use of SAP. Hence Antimicrobial stewardship (AMS) interventions such as periodic audits and educational interventions should be implemented to improve the appropriate use of SAP and to prevent the emergence of AMR.
K. Shailaja *, D. Fragrance Jemimah, L. S. Aritta Hillari and N. Priyanka
Department of Pharmacy Practice, C. L. Baid Metha College of Pharmacy, Affiliated to the Tamil Nadu Dr. MGR Medical University, Thoraipakkam, Chennai, Tamil Nadu, India.
22 August 2022
21 October 2022
18 November 2022
01 June 2023