ANTI-DIARRHOEAL ACTIVITY OF METHANOLIC EXTRACT OF ROOT BARK OF AILANTHUS ALTISSIMA SWINGLE (FAMILY: SIMAROUBACEAE) ON EXPERIMENTAL ANIMALS
AbstractAilanthus altissima Swingle (Simaroubaceae) is commonly known as “Tree of heaven”. The methanolic extract of root bark of A. altissima (MEA) was taken for anti-diarrhoeal activity. Investigations were carried out on castor oil induced diarrhoea and small intestine transit method on mice. In former method, MEA 200 (mg/Kg) were reducing the total weight of the faeces of group (0.163±0.028) in comparison to control group faeces (0.652±0.041), were statistically significant (P<0.001). In latter method, the MEA 200 (mg/Kg) inhibited 72.414% of the distance travelled by the charcoal and were significant statistically (P<0.001).
Article Information
26
197-202
398 kB
1319
English
IJPSR
Munesh Mani*, Neetu Sachan, Ankita Tandon, Arun Kumar Wahi
College of Pharmacy, Institute of Foreign Trade and Management (IFTM), Moradabad (UP), India
29 July, 2010
24 October, 2010
09 November, 2010
http://dx.doi.org/10.13040/IJPSR.0975-8232.1(12).197-02
01 December, 2010
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