ANTI- INFLAMMATORY, ANALGESIC & ULCEROGENIC ACTIVITY OF KETOPROFEN GLUCOPYRANOSIDE CONJUGATES
AbstractKetoprofen is a non-steroidal anti-inflammatory drug. Glucopyranoside Conjugates of Ketoprofen have been synthesized and evaluated for anti- inflammatory, analgesic and ulcerogenic activities. In vivo biological screening in mice and rats indicated that conjugates improved analgesic and anti-inflammatory activities with significantly reduced ulcerogenicity compared to the parent drug.
Article Information
11
96-101
428 kB
1048
English
IJPSR
Jagdish K. Sahu * , A. Kaushik and L. Banerjee
Institute of Professional Studies College of Pharmacy, Gwalior (MP), India
jagdish.pharmacist@gmail.com
28 January, 2010
20 February, 2010
25 February, 2010
http://dx.doi.org/10.13040/IJPSR.0975-8232.1(4).96-01
01 April, 2010