ANTIBACTERIAL AND ANTIVIRAL PROPERTIES OF SILVER NANOPARTICLES SYNTHESIZED BY MARINE ACTINOMYCETESAbstract
Present work has been conducted to evaluate antibacterial and antiviral activity of silver nanoparticles using marine Actinomycete, Nocardiopsis alba, isolated from mangrove soil. Formation, size, and shapes of silver nanoparticles (AgNPs) were characterized by UV-visible spectroscopy, X-Ray Diffraction (XRD), FTIR and Transmission electron microscope (TEM). From the UV-visible spectroscopy, the absorption peak was found at 420 nm. The SEM images confirmed that the sample contains spherical silver nanoparticles. The XRD analysis confirmed that the silver nanoparticles are crystalline, which was confirmed by the FT-IR peak at 564 cm-1 corresponding to the silver nanoparticles vibration present in the crystalline structure. The silver nanoparticles have significant antibacterial activity against Pseudomonas aeruginosa, Klebsiella pneumonia, Streptococcus aureus, and E. coli. and antiviral activity against new castle viral disease (NDV) in cattle The findings of the present study suggest that the silver nanoparticles possess a good antibacterial a d antiviral activity and could have great importance as a therapeutic agent in current nanomedicine.
J. Avilala and N. Golla *
Department of Virology, Applied Microbiology Laboratory, Sri Venkateswara University, Tirupati, Andhra Pradesh, India.
26 June 2018
28 September 2018
29 October 2018
01 March 2019