ANTIMICROBIAL ACTIVITY OF BURSERA PENICILLATA LEAF EXTRACTS ON HUMAN INFECTIOUS PATHOGENSAbstract
The purpose of this study was to evaluate antimicrobial activity of Bursera penicillata leaf extract against human infected bacteria. Antimicrobial activity of Petrolium ether, Methanolic and Aqueous extracts from leaves of Bursera penicillata were tested against pathogenic bacteria Staphylococcus aureus, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae, Staphylococcus saprophyticus, Enterococcus faecalis and Enterobacter cloacae using Agar well diffusion method. Solvent extracts from the leaves of the plant shown a considerable antimicrobial activity against most tested microorganisms. The most active extract was Methanolic extract from the leaf against Klebsiella pneumoniae and significantly inhibited the bacterial activity. Minimum inhibitory concentration for aqueous and methanolic extracts of leaves ranged from 5.0–20.0 mg/ml and ethyl acetate and petroleum ether leaf extracts ranged from 25.0µg-55.0 µg and 45.0-85 µg/ml. It further reflects a hope for the development of many more novel chemotherapeutic agents or templates from such plants which in future may serve for the production of synthetically improved therapeutic agents.
T. Ashok *, N. Madhuri, G.L.N Raju and M. Rani
Department of Microbiology, Ventura Institute of Biosciences1, Moosaram Bagh, Hyderabad, Telangana, India.
05 July, 2014
10 October, 2014
19 January, 2015
01 February, 2015