ANTIMICROBIAL ACTIVITY OF UNCOMBINED AND COMBINED EXTRACTS OF DOLIOCARPUS DENTATUS AND MONTRICARDIA ARBORESCENS

The antimicrobial activity of the individual extracts of Doliocarpus dentatus and Montricardia arborescens and combined extracts of both plants were investigated against bacterial strains E. coli, S. aureus and K. pneumoniae using the Disc/ Agar Diffusion method under asceptic conditions. The magnitude of the diameter of the zone of inhibition was used as an indication for antimicrobial susceptibility or potency. Aqueous and C₂H₅OH extract of Doliocarpus dentatus showed insignificant antimicrobial activities whereas the CH₂Cl₂ and EtOAC extract of Doliocarpus dentatus were antimicrobial. The area of zone of inhibition ranging from 68.3 mm² to 89.4 mm². However, all the extracts of Montricardia arborescens were antimicrobial against all three bacterial strains. The area of zone of inhibition ranging from 68.3 mm² to 172.6 mm². The combined extract also showed variation in potency against the three microbial strains with the area of zone of inhibition ranging from 180 mm² to 368.6 mm².