ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF PEELS, PULPS AND SEED KERNELS OF THREE COMMON MANGO (MANGIFERA INDICAL L.) VARIETIES IN SRI LANKA

Mango products are well demanded by consumers due to their unique flavor and mango pulps are developed as various products while mango peels and seeds are the major agro-industrial wastes in canned fruit manufacture and fruit juice processing. Hence the aim of the present study was to investigate on their bioactive phenolic compounds in mango byproducts. Extracts of pulps, seed kernels and peels were prepared using ethyl acetate. Total phenolic content (TPC), total flavonoid content (TFC), antioxidant activity and the anti-inflammatory activity were evaluated. The higher TPC was observed in the peels (52.67-275.61 mg GAE/ g of extract) and the seed kernels (132.95-270.56 mg GAE/ g of extract) than that of the pulp while the highest TFC was present in the pulps (120.20-479.80 mg QE/g of extract). The extracts of mango seed kernels and peels exhibited greater antioxidant activity on DPPH, ABTS, NO, FRAP assays and higher anti-inflammatory activity with IC₅₀ values of seed kernel and peel extracts were found in the range of 7.73-222.10 µg/mL and 11.86 to 197.29 µg/mL respectively. The present study demonstrates significantly high antioxidant and anti-inflammatory potential uses of mango byproducts as sources of bioactive compounds.