ANTIPYRETIC ACTIVITY OF AQUEOUS AND ALCOHOLIC EXTRACTS OF NONI ON YEAST INDUCED PYREXIA IN RATS
AbstractNumerous herbal agents have been claimed to having antipyretic property. One up-coming botanical fruit of Morinda citrifolia, whose Polynesian name is Noni, is unique in view of the large number of medical indications that characterize claims for its efficacy. Researchers at an independent research facility found that Noni was a selective inhibitor of COX-2 enzyme. The analgesic efficacy of the Noni extract is 75 % as strong as morphine. Thus the present study was planned to study the antipyretic activity of aqueous & alcoholic extracts of Noni on yeast induced pyrexia, a model for experimentally induced pyrexia in albino rats. The alcoholic extract of Noni has been found to produce more significant antipyretic activity after 2nd, 3rd and 4th hours of administration
Article Information
40
1850-1854
434
1169
English
Ijpsr
Bharti Jethani , R. K. Sharma*, M. Raipuria , Hemlata Jain
Associate Professor, Department of Pharmacology and Toxicology, College of Veterinary Science and Animal Husbandry, Mhow, Madhya Pradesh, India
17 April, 2011
03 June, 2011
16 June, 2011
40. http://dx.doi.org/10.13040/IJPSR.0975-8232.2(7).1850-54
01 July, 2011
Download