APPLICATION OF DESIGN OF EXPERIMENTS FOR OPTIMIZATION OF RANEY NICKEL MEDIATED BORROWING HYDROGEN REACTION
AbstractAn efficient, cost effective use of Raney nickel (R-Ni) a widely used industrial catalyst for N-Alkylation using alcohols is highlighted here. The work describes the scope and capability of R-Ni in borrowing hydrogen reactions for Aniline and Benzyl alcohol. The reaction optimization is described using two techniques, Conventional and Design of experiment. The use of DOE for reaction optimization is an unique option described in this paper.
Article Information
32
746-751
451KB
1699
English
Ijpsr
Astha Mehta , A. Thaker , V. Londhe and Santosh R. Nandan *
Ambernath Organics Pvt ltd, 307/314, Creative Industries Premises, Road No.2, Sunder Nagar, Kalina, Mumbai-400098, India.
santosh.nandan@gmail.com
18 June, 2014
28 August, 2014
17 October, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).746-51
01 February, 2015
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