ARTEMISIA ANNUA (QINGHAO): A PHARMACOLOGICAL REVIEWAbstract
Artemisia annua L., also known as sweet wormwood, sweet annie, sweet sagewort and annual wormwood (Chinese: qngho), is a common type of wormwood that is native to temperate Asia, but naturalized throughout the world, and that belongs to the family of the Asteraceae. Currently, Artemisia annua is the source for the production of artemisinin and semi-synthetic artemisinin derivatives (including dihydroartemisinin, artesunate, artemether and arteether) that are used for the production of combination therapies for treatment of malaria (ACTs = Artemisinin-based Combination Therapy). Animal studies suggested that artemisinin and related compounds inhibit tumor growth and metastasis. However, there is no reliable evidence from clinical trials at the moment that effects from animal studies translate into benefits for cancer patients. Experiences from malaria treatment indicate a good tolerability of artemisinin-based drugs. However, there are two case reports with severe adverse effects if artemisinin-based drugs were used at higher doses.
Department of Pharmacology, NSHM College of Pharmaceutical Technology, 124, B.L. Saha Road, Kolkata 700053, West Bengal, India
03 August, 2012
17 September, 2012
16 November, 2012
01 December, 2012