ASSESSMENT OF THE PRESCRIPTION PATTERN OF ORAL HYPOGLYCEMIC DRUGS IN UNCOMPLICATED DIABETES MELLITUS PATIENTS AT TERTIARY CARE HOSPITAL

Aim and Objective: Drug utilization research help in identification of the clinical use of drugs in population and its impact on health care system and to evaluate the rational drug usage. To study prescription pattern, to evaluate the adherence to treatment guidelines in diabetic patients attending the medical outpatient department in a tertiary care teaching hospital. Drug utilization research help in identification of the clinical use of drugs in population and its impact on health care system. To select the rational use of drugs as a predominant technique for the utilization of selective drugs in diabetes mellitus patients. Methodology: A cross-sectional retrospective study was carried out for 6 months in diabetic patients in the General Medicine Department. Data of 280 patients were collected and evaluated. Results: Total 280 diabetes mellitus patients were admitted. In this study, almost all prescriptions were with polypharmacy. The pattern of drug prescription in diabetes mellitus shows that insulin (22.14%) was most frequently prescribed followed by glimepiride (16.78%) and metformin (8.21%). In sulfonylureas monotherapy are 50.7%, a combination of two drugs are 21% and the combination of three drugs is 2.14%. Combination therapy was prescribed to 44.41% and monotherapy to 52.48% of patients; 54.28% of these patients were male and 45.71% were female. Conclusion: Glimepiride and insulin have been most frequently prescribed, before prescribing to the patients, evaluation of medications with the suitable criteria is required. In other words, rational use drug must be strictly followed.