BIOMARKER LANDSCAPE OF MYCOSIS, WITH SPECIAL EMPHASIS ON MUCORMYCOSIS
AbstractSystemic fungal infections, including opportunistic and endemic mycoses, pose a significant threat to immunocompromised individuals. Mucormycosis, caused by zygomycetes, is particularly devastating, characterized by tissue necrosis and diverse clinical manifestations. Risk factors such as immunodeficiency and underlying diseases contribute to its incidence. Through a comprehensive literature analysis, this review examines existing data on mucormycosis biomarkers. Treatment typically involves aggressive antifungal therapy and surgical debridement. Promising biomarkers like galactomannan and mannan are identified for early detection and monitoring, crucial for improving diagnostic accuracy and facilitating timely interventions. Pursuing biomarkers for systemic mycoses is crucial for enhancing infection management. Early detection through biomarkers has the potential to decrease morbidity and mortality associated with mucormycosis, ultimately improving outcomes for vulnerable patients.
Article Information
3
2210-2221
978 KB
322
English
IJPSR
V. Poorna Harika and Richa Jain *
Department of Biotechnology and Microbiology, Centre for Scientific Research and Development, People's University, Bhopal, Madhya Pradesh, India.
richa198@gmail.com
01 February 2024
02 April 2024
17 May 2024
10.13040/IJPSR.0975-8232.15(8).2210-21
01 August 2024
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