CARDIOVASCULAR DISEASE MANAGEMENT IN A TERTIARY CARE HOSPITAL

Background: The study assesses pharmacological management of CAD in a tertiary care center, focusing on medication adherence and quality of life (QOL) among hypertensive female patients. Materials and Methods: A prospective observational study conducted at LPS Institute of Cardiology, GSVM Medical College, Kanpur, included 140 diagnosed CAD patients between September 2021 to November 2022. Results: Among 140 participants, 55 patients (39.3%) presented with Acute Coronary Syndrome (ACS): 35 with STEMI and 20 with NSTEMI/UA. The remaining 85 patients had stable angina, underwent diagnostic coronary angiography, or were admitted for post-intervention follow-up, indicating a broader representation of CAD spectrum in clinical settings. The age group 61–70 years was most affected (32.86%). Hypertension (64.3%), diabetes (48.6%), and smoking (29.3%) were the major risk factors. Statins (94.29%), clopidogrel (89.29%), aspirin (86.43%), beta-blockers (60%), and ACE inhibitors (53.57%) were the most prescribed medications. The analysis of QOL domains showed a positive association between medication adherence and physical, psychological, social, and environmental well-being. Conclusion: Adherence to evidence-based pharmacological therapy was high, but underutilization of ACE inhibitors and lack of combination therapy remain concerns. Age-stratified risk and medication usage patterns suggest a need for personalized and accessible care.