COMPREHENSIVE REVIEW ON ACNE VULGARIS AND ITS TREATMENT

Acne vulgaris is a multifactorial skin disorder of pilosebaceous unit which majorly affects teenagers, but it can continue into adulthood and cause aesthetical as well as psychological problems. This review article enlightens the knowledge related to cause and treatment of acne vulgaris. Several factors which are involved in the development of acne vulgaris are hormonal activity, sebum production, follicular epidermal hyperproliferation, colonization with Propioni-bacterium acnes (P. acnes) and inflammation. There are several treatment methods available for acne, although some new therapeutic agents have been introduced during the last few years; synthetic drugs still remain the best option in the treatment of acne. However, rapid appearance of antibiotic resistance and high re ocurrence rates have led to a search for alternatives in nature. The use of herbal drugs in prevention and treatment of acne vulgaris nowadays increased because of their efficiency, availability and lesser side effects than synthetic drugs. Some common used topical herbal remedies with significant anti-inflammatory activities antimicrobial activities have mentioned in this review article include tea tree oil (Melaleuca alternifolia), turmeric (Curcuma longa), neem (Azadirachta indica), licorice (Glycyrrhiza glabra), lavender (Lavandula angustifolia), green tea (Camellia sinensis) and basil (Ocimum basilicum). Other commonly utilized effective synthetic drugs discussed in this include benzoyl peroxide, azelaic acid and retinoids etc. This review article provides complete knowledge about cause factors and treatment options which are available for acne vulgaris patients.