CORRELATION OF THE LEVELS OF HIGH SENSITIVITY C-REACTIVE PROTEIN (hs-CRP) IN PATIENTS DIAGNOSED WITH METABOLIC SYNDROME

Objectives: Metabolic syndrome (MetS) is a cluster of several metabolic disorders including hyperglycemia, reduced high density lipoprotein cholesterol (HDL-C), raised triglyceride level in serum, hypertension and abdominal obesity. The independent risk factors of high sensitivity C-reactive protein (hs-CRP) levels may have a significant impact on evaluating the preva­lence of MetS components in both men and women. Methods:  The present study was conducted at Shri Ramkrishna Institute of Medical Sciences and Sanaka Hospital, Durgapur, West Bengal. The study includes 100 patients with MetS as a case and 100 healthy volunteers as a control. MetS was diagnosed according to international diabetes federation. Results: In our study the level of hs-CRP is high in metabolic syndrome patients (4.88 μg/ml) compared to control group is (1.699 μg/ml) A statistically highly significant difference was observed among two groups (p<0.000). Conclusions: The level of hs-CRP maybe used as a surrogate marker of chronic inflammation in metabolic syndrome patients and higher levels of the inflammatory marker hs-CRP are correlated with rise risk for development of cardiovascular disease and diabetes mellitus.