DRUG USE EVALUATION OF BRONCHODIALATORS IN PAEDIATRICS IN A TERTIARY CARE HOSPITALAbstract
The use of bronchodilators has been increasing for the past few decades. The literatures have reported a high rate of adverse events. It has also been found out that beta-agonists are associated with an increased morbidity and mortality rate. Respiratory tolerance develops due to regular use of beta-agonists, which are widely prescribed in asthma and bronchiolitis also is of major concern.
Objective: To evaluate the rational use of bronchodilator drugs by analyzing the appropriateness of the prescription.
Methodology: Prospective observational study.
Study site: A 500-bedded Multispecialty Tertiary care Teaching Hospital. Result: In the study population of 133 patients male children were found to be more (58.6 %) than the female children (41.4%) Most of the bronchodilators were prescribed for infants (48.1%). Of the 133 pediatric patients, the major prescription was for SABA (99.2%). Of which the major prescription was for salbutamol (63.2%). Most of the Children with asthma were prescribed with combination therapy of salbutamol and ipratropium (81.3%). In WALRI, patients were prescribed with salbutamol (40.4%) and in acute bronchiolitis, the major prescription was found to be salbutamol and ipratropium combination (70.3%). In 52.6% of the prescriptions bronchodilator were given by nebulization and oral route. 31.6% were given by nebulization. 95.5% of patient was prescribed with antibiotics along with bronchodilators, followed by mucolytics 55.6%. Asthma action plan and patient education were not provided by healthcare providers.
K.M. Binu, Nimmy N. John, Alan Lee Mathew, H. Doddayya and Ashok Kumar Malpani
Department of Pharmacy Practice, N.E.T. Pharmacy College, Raichur, Karnataka, India
22 May, 2012
17 July, 2012
23 September, 2012
01 October, 2012