DRUG UTILISATION EVALUATION OF ANTI HYPERTENSIVE DRUGS IN CHRONIC KIDNEY DISEASE PATIENTS

Objective: To assess the drug utilization evaluation of antihypertensive agents in diabetic and non-diabetic patients with chronic kidney disease. Method: Retrospective observational study was conducted in inpatient Nephrology department of B.B.R. Hospital from Sep 2016 to Feb 2017 and 155 case records of patients diagnosed with CKD and HTN, above 18 yrs of age, belonging to both genders were collected. Required Information from the patient’s case sheets was collected using a well designed data collection form. Results: The prevalence of CKD is more in male than in female and most commonly age group of > 60 yr was affected with CKD. Our study showed that majority of patients needed multiple drug therapy to control hypertension. Diuretics were most commonly prescribed drugs. The preferable drugs given among anti-hypertensive were diuretics, calcium channel blockers, beta blockers, alpha blockers, ARB’S. Conclusion: Most of the CKD patients were Male (63.87%) in distribution. Of the 155 cases, 69.03% of patients were also suffering from diabetic. Majority of patients (both diabetic and non-diabetic hypertensive patients with CKD) were prescribed with Diuretics (40.71%), of which Furosemide (31.12%) was predominantly seen. 65% of prescribed drugs were brand name drugs. Polypharmcy was observed in most of the prescriptions.