EVALUATION OF ANTIHELMINTHIC ACTIVITY OF KALANCHOE PINNATA LEAVES
AbstractIn this study, the anthelmintic activity of Kalanchoe pinnata leaves extract against Indian earthworm Pheretima posthuma was evaluated and compared with the standard drug Albendazole. This activity was concentration dependent. As the concentration increases the extract produce maximal effect. Higher concentrations of ethanolic leaf extract of Kalanchoe pinnata produce a paralytic effect much earlier and time taken for death was shorter. It shows maximum efficacy at 100 mg/ml concentration than the standard drug. The results indicated that the extract had significant anthelmintic activity, as demonstrated by the time of paralysis and death of worms. These findings suggest that Kalanchoe pinnata leaves extract could be a promising natural anthelmintic agent. Further research is recommended to isolate and identify the active principles responsible for its activity, which could lead to the development of new drugs for the treatment of worm infections. This study provides valuable information on the medicinal properties of Kalanchoe pinnata and highlights the potential of natural products as an alternative to conventional drugs for managing parasitic infections.
Article Information
30
253-256
613 KB
271
English
IJPSR
J. Hima Bindhu *, P. Rajyalakshmi, T. Srija, V. Ramya Sree, P. Devendar and K. Ramanjaneyulu
Department of Pharmaceutical Chemistry, Vishnu Institute of Pharmaceutical Education and Research, Narsapur, Medak, Telangana, India.
himabindu.chem@gmail.com
15 May 2023
10 July 2023
21 November 2023
10.13040/IJPSR.0975-8232.15(1).253-56
01 January 2024
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