EVALUATION OF ANTIMICROBIAL ACTIVITY OF SESUVIUM PORTULACASTRUM (L.) L. AND EXCOECARIA AGALLOCHA L.

Background: Sesuvium portulacastrum L. and Excoecaria agallocha (L.) are two important medicinal plants inhabited in mangrove regions. Early researches focused on antimicrobial activity of leaves of concerned plants with various solvents among which ethanol, chloroform, and methanol were the best Objective: In the present study the extracts of two therapeutic plants were researched to measure the activity against 2 Gram-positive bacteria, 2 Gram-negative bacteria and 3 fungal strains. Materials and Methods: Hexane, Ethyl acetate, and Methanol were utilized for extraction. Bacterial Strains Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, Pseudomonas aeruginosa, and fungal strains Aspergillus niger, Aspergillus flavus, Aspergillus fumigatus were used to test the antimicrobial activity. Results: The activity increased in dose dependent manner thus hexane concentrate of Sesuvium portulacastrum display most noteworthy action against P.aeruginosa and E. coliand Aspergillus flavus demonstrated maximum. Excoecaria agallocha show the highest zone against S. aureus, and P. aeruginosa demonstrated the least movement. Hexane was demonstrated best dissolvable for Sesuvium portulacastrum and Excoecaria agallocha. Ethyl acetate was finest for the fungal activity of both plants.  Conclusion: These outcomes bolster the thought that therapeutic plants may have a job as pharmaceuticals and additives.