EVALUATION OF SERUM VITAMIN D AND VARIOUS ORGANS FUNCTION TESTSIN DIFFERENT TRIMESTERS OF PREGNANCY: A SYSTEMATIC REVIEW
AbstractBackground: Vitamin D is a lipid-soluble vitamin that plays an important role in maintaining calcium and phosphorus homeostasis and promoting bone metabolism. It sustains normal values of calcium and phosphorus in the systemic circulation. If the exogenous calcium sources are insufficient, vitamin D together with the parathyroid hormone (PTH) will direct part of the bone calcium. Circulating serum 1, 25(OH)2 D gradually increases during the 1st and 2nd trimesters, owing to an increase in Vitamin D-binding protein concentrations in the maternal circulation. However, it is the free levels of 1, 25(OH)2 D, which are actually responsible for enhancing transport of calcium across the placenta. Hormonal changes initiated even before conception significantly alter maternal biochemistry early in pregnancy. Steroid hormones, peptide hormones and prostaglandins interact to expand blood and plasma volume and modulate the maternal capacity to supply energy and nutrients to the fetoplacental unit.
Article Information
14
3337-3344
558 KB
269
English
IJPSR
Satya Prakash *, Raj Kumar and Indra Prasad Adhikari
Department of Biochemistry, BRD Medical College, Gorakhpur, Uttar Pradesh, India.
harshaladhikari@gmail.com
08 October 2022
02 May 2023
30 May 2023
10.13040/IJPSR.0975-8232.14(7).3337-44
01 July 2023
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