EVALUATION OF STRESS IN EXPERIMENTAL PHARMACOLOGYAbstract
Stress undoubtedly has become an integral part of human life. Stressful conditions have a derogative effect on normal physiological functions leading to a variety of disease states. Many of the most prevalent diseases of the modern era like hypertension, diabetes, behavioral disorders, etc. have been implicated as one of the many ill-effects of chronic stress. Experimental models are required to better understand the progression of the disease and elaborate new therapy. Therefore a need to develop animal models of stress has always been realized. An ideal model should be able to reproduce each of the aspects of stress response and should be able to mimic the natural progression of the disease. Unfortunately different models of stress that have been used are able to evaluate some of the many biochemical or physiological parameters that get altered as a response to stress but are unable to fully mimic the patho-physiological changes caused by stress.
Nitish Bhatia*, Partha Pratim Maiti , Abhinit Choudhary , Atul Tuli , Daljit Masih , Mohd. Masih Uzzaman Khan , Tasneem Ara and Amteshwar Singh Jaggi
DISM, Assistant Professor, Sri Sai College of Pharmacy, Badhani, Pathankot, Panjab, India
11 January, 2011
18 March, 2011
18 April, 2011
01 May, 2011