EXTRACTION OF FUCOXANTHIN FROM SARGASSUM WIGHTII, FTIR SPECTRA AND IT’S ANTIOXIDANT AND ANTIBACTERIAL PROPERTIES

Sargassum wightii,a seaweed and a marine macroalgae, is known to offer numerous health benefits, and compounds isolated from it are observed as the alternative to conventional treatment as an affordable plant-derived drug. In the present study, the bioactivity of the two fractions from Sargassum wightiiw as derived using two different solvents, methanol and acetone: methanol. Acetone: Methanol fraction showed better yield. Both the fractions it was tested against both gram-positive Staphylococcus aureus and gram-negative Escherichia coli bacteria. The antioxidant potential was evaluated by the reducing power assay. Fucoxanthin extracted by maceration in methanol: acetone (9:1) showed more excellent antioxidant activity. The partially purified extract was also analysed through the FT-IR spectra. The extract prepared by methanol: Acetone extract performed better than streptomycin, but compared to streptomycin, none of the extracts showed significant antibacterial action at higher concentrations. The FT-IR spectra showed various secondary metabolites and their derivatives in the crude extracts.