FORMULATION AND EVALUATION OF BOSWELLIC LOADED TRASFEROSOMES HYDROGEL TO TREAT PSORIASIS
AbstractTransfersomes, which may penetrate mammalian skin, are notably ultra deformable (ultraflexible) lipid supramolecular aggregates. A type of formulation carrier system called a transfersome can transport medications with both low and high molecular weights transdermally. Transfersomes enter the underlying viable skin in an undamaged state through skin’s stratum corneum pores that are smaller than its size. The major goal of the transferosome in treating the condition psoriasis is drug penetration through the skin. However, the stratum corneum is the most formidable defence against drug penetration via the skin. In order to assist penetrate the stratum corneum barrier, the use of lipid vesicles like transfersomes in delivery systems has attracted increasing interest in recent years. The current study set out to statistically improve the vesicular formulations (Transfersomes) of a model medicine, boswellic acid which is obtained from Boswellia serreta known as for the treatment of psoriasis.
Article Information
45
4054-4060
825 KB
347
English
IJPSR
Surbhi Sirswal * and Sanjay Singh
Siddhartha Institute of Pharmacy, Veer Madho Singh Bhandari Uttrakhand Technical University, Dehradun, Uttrakhand, India.
Surbhisirswal23@gmail.com
07 December 2022
22 February 2023
02 May 2023
10.13040/IJPSR.0975-8232.14(8).4054-60
01 August 2023
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