FUNCTIONAL GENOMICS OF MYCOBACTERIUM TUBERCULOSIS
AbstractMycobacterium tuberculosis is a deadly infectious disease, there is rising death of humans every year because of this disease, availability of genome sequences of Mycobacterium tuberculosis has provided tremendous amount of information that can be useful in drug target and new vaccine development. Sequence similarity provides accurate annotation for genes in newly sequenced genomes. In this present work about 107 hypothetical proteins of Mycobacetrium tuberculosis were taken and its functions were predicted using bioinformatics tools BLAST, BLOCKS, COGs, InterProScan and PFP. From our analysis of 107 hypothetical proteins only two shows 100% functions these proteins may serve as target for few antibiotics
Article Information
32
1793-1798
681
1134
English
Ijpsr
Anitha Jabamalai Raj , Sangilimuthu Algar Yadav , Velliyur Kanniappan Gopalakrishnan , Akila Selvaraj and Sudarsanam Dorairaj*
Department Advanced Zoology and Biotechnology, Medical lab Technology & Biomedical Instrumentation ScienceLoyola College, Chennai-600034, India
11 April, 2011
14 May, 2011
26 June, 2011
http://dx.doi.org/10.13040/IJPSR.0975-8232.2(7).1793-98
01 July, 2011
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