GC-MS PROFILING AND ANTHELMINTIC ACTIVITY OF ANTIGONON LEPTOPUS LEAVES
AbstractThe study was designed to determine the phytocomponents and in-vitro anthelmintic activity of chloroform fraction of methanolic extract of Antigonon leptopus leaves. GC-MS analysis of chloroform fraction of the methanolic extract of Antigonon leptopuswas performed on a GC–MS equipment (Thermo Scientific Co. Thermo GC-TRACE ultra ver.: 5.0, Thermo MS DSQ II). The extract under study has been screened for anthelmintic activity on Pheretima posthuma. The chloroform fraction was analysed by GC-MS which revealed the presence of many diversified compounds including phenols, hydrocarbons, quinazolines, coumarins, steroids and terpenes like cadinene, juniper camphor etc. All the compounds were identified from Wiley spectral library. Mass spectral data of 16 compounds is presented. The results obtained from the study indicate significant anthelmintic activity, supporting folk use of the plant when compared with the standard. From the results, it is evident that Antigonon leptopus contains various bioactive compounds and biological activity which is recommended as a plant of phytopharmaceutical importance.
Article Information
38
1914-1918
370KB
2195
English
IJPSR
K. Sony Priya, K. Satyavathi, P. Bhojaraju, Y. Ratna Kumari, D. Venkatesh Prasad, M. Sesha Sai Durga, P. Mercy Preeti, K. Pardhava Lovaraju and Lakshmi Kanta Kanthal*
M. Pharma, AIC, (Ph. D), Associate Professor, Koringa College of Pharmacy, Department of Pharmacology, Korangi-533461, Tallarevu Mandal, East Godavari Dist., Andhra Pradesh, India
lkkhaldia@gmail.com
08 December, 2013
11 January, 2014
09 March, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.5(5).1914-18
01, May 2014
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