HEPATOPROTECTIVE EFFECTS OF POLYHERBAL FORMULATION AGAINST CARBON TETRACHLORIDE-INDUCED HEPATIC INJURY IN ALBINO RATS
AbstractObjective: To investigate the hepatoprotective activity of polyherbal formulation composed of extracts of Bauhinia variegata, Oxalis corniculata, and Pterocarpus marsupium. Methods: The hepato-protective activity of the formulation and extracts were assessed on the basis of histopathological changes in the liver and estimation of SGOT, SGPT, SALP, serum bilirubin of carbon tetrachloride-induced hepato-toxic rats. Results: The result of the present studies strongly indicates that the hepatoprotective property of polyherbal formulation is evidenced by less damaged hepatocytes cells. Conclusion: Polyherbal formulation composed of aqueous extracts of Bauhinia variegata, Oxalis corniculata, and Pterocarpus marsupium revealed significant hepatoprotective profile as compared to standard formulation Liv-52.
Article Information
48
4465-4475
886
529
English
IJPSR
A. G. Jadhav and R. S. Dhikale *
Department of Pharmacognosy, Sandip Institute of Pharmaceutical Sciences, Nashik, Maharashtra, India.
rupadhikale@gmail.com
28 August 2020
03 February 2021
19 May 2021
10.13040/IJPSR.0975-8232.12(8).4465-75
01 August 2021
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