IN VITRO ANTI-INFLAMMATORY ACTIVITY OF VARIOUS EXTRACTS OF LEAF AND BARK OF HOLOPTELIA INTEGRIFOLIA PLANCH
AbstractThe different extracts of leaf and bark of the plant Holoptelia integrifolia were investigated for in-vitro anti-inflammatory activity by human red blood cell membrane stabilization (HRBC) method. The HRBC membrane stabilization activity of the petroleum ether extract of leaf at the concentration of 200 mg/ml showed 68.12+/-1.05 % and petroleum ether extract of bark at the concentration of 200 mg/ml showed 71.25+/-1.72 %. Inhibition of denaturation in hypotonic solution with standard Diclofenac sodium 100 mg/ml showed 79.25%. Therefore, these extracts showed equipotent activity to Diclofenac sodium
Article Information
47
2987-2990
265
1169
English
IJPSR
Padmaja , Chinna Eswaraiah and Amgoth Srinivas Nayak*
University College of Pharmaceutical Sciences, Satavahana University, Karimnagar-505001, Andhra Pradesh, India
nayak_as@yahoo.co.in
01 February, 2014
30 March, 2014
03 May, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2987-90
01 July, 2014