IN-VITRO CYTOTOXIC STUDY OF NATURAL POLYSACCHARIDE ISOLATED FROM T. CORDIFOLIA FRUIT
AbstractThe polysaccharide-derived polymers can play an integral and versatile role in the novel drug delivery system for a variety of therapeutic agents in the biological system. In this research, natural polysaccharide isolated to evolve natural polymer-based innovative drug delivery carriers to provide maximum therapeutic effect and minimize clinical complications, which could also be a step towards biological environment-friendly drug delivery systems since the envisaged natural polymer could be a good substitute compared to the synthetic polymers currently used for novel drug delivery systems with modified drug delivery properties. Tinospora cordifolia is a tropical herb of the Menispermaceae family, also known as ‘Guduchi’, well-known for its therapeutic benefits in the Indian traditional system. This plant’s fruits cluster in groups of one to three, and the mucilage contains complex polysaccharides. In-vitro cytotoxicity studies on fibroblast cells revealed about 80% cell viability, confirming its biocompatibility as a natural excipient with potential applications in green and advanced pharmaceutical drug delivery systems.
Article Information
31
1340-1345
702 KB
12
English
IJPSR
Noopur Verma and Ajay Kumar Gupta *
School of Pharmaceutical Science (formerly University Institute of Pharmacy), Chhatrapati Shahu Ji Maharaj University (formerly Kanpur University) campus, Kanpur, Uttar Pradesh, India.
ajaykumargupta@csjmu.ac.in
28 November 2025
19 March 2026
20 March 2026
10.13040/IJPSR.0975-8232.17(4).1340-45
01 April 2026
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