INFLUENCE OF THE SEASONAL CHANGES AND OF THE EXTRACTION METHOD ON FLAVONOID CONTENT IN PEPEROMIA PELLUCIDA L. (H.B.K.)
AbstractDuring the obtainment of herbal products, standardization of raw plant materials is ensured by the quality of herbal drugs, of the extraction conditions, followed by the determination of the content of one or more components or of the most representative compounds of their composition, which are adjusted to values previously defined, resulting in greater uniformity of plant derivatives, important for the production of safe and effective medicines. This study aimed to analyze the marker (3′, 4′, 7-tri-O-methoxyflavone) content of Peperomia pellucida L. (HBK) in three periods of collection in order to assess the seasonal changes and different extraction methods (maceration and percolation) with different solvent concentrations. The highest incidence of rain over a given period does not influence the marker content present in the sample. The maceration using 70% of ethyl alcohol obtained the highest marker content value.
Article Information
8
354-360
381KB
1206
English
IJPSR
Rosali Maria Ferreira da Silva*, Thays Cristiane Barbosa de Lucena Gomes , Giovanna Chistinne Rocha de Medeiros , Monize Santos Peixoto , Evelyn Mirella Lopes Pina, Salvana Priscylla Manso Costa, Manolo Cleiton C. de Freitas , Milton Nascimento Silva , Mara Sílvia Pinheiro Arruda , Pedro José Rolim Neto
Technology Laboratory of Medicine - Department of Pharmaceutical Sciences, Federal University of Pernambuco, Professor Arthur de Sá Street, s/n, Cidade Universitária, 50740-521 Recife - PE, Brazil
rosalimfs@ibest.com.br
03 September, 2013
21 November, 2013
09 January, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.5(2).354-60
01 February, 2014
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