“MITREС” AS AN EFFECTIVE DRUG FOR THE TREATMENT OF COWS WITH CHRONIC ENDOMETRITIS

The leading factor restraining the intensification of herd reproduction is endometritis. The article states that the microflora of cow uterine exudate in chronic purulent-catarrhal endometritis is represented by Staphylococcus aureus, Escherichia coli, Proteus vulgaris, Citrobacter freundii, Streptococcus faecalis, Streptococcus faecium, as well as anaerobes and group С Streptococci. The drug “Mitreс” showed the greatest effectiveness of suppressing the growth of the majority of isolated strains of microorganisms. Its zone of growth inhibition was as follows: Streptococcus faecium – 31 ± 2.06 mm, Citrobacter freundii – 30 ± 0.00 mm, anaerobes – 29 ± 0.00 mm, Proteus vulgaris – 28.5 ± 1.72 mm, Escherichia coli – 27.0 ± 1.45 mm; group C Streptococci– 27.32 ± 2.12 mm; Staphylococcus aureus strains- 25.5 ± 1.66 mm; Streptococcus faecalis– 25.0 ± 1.12 mm. The recovery of cows with chronic purulent-catarrhal endometritis after applying “Tilozinocarum” was 80%, “Endometramag-T” showed 90%, and mitrec demonstrated 100% recovery. During the 90 days of observation of the experimental group of cows injected with the drug “Sepranol” fertilization occurred in 13 animals (65%); insemination index was 4.1. Under Endometramag-T treatment fertilization occurred in 18 animals (90%); insemination index was 2.6. With tilozinocarum 16 females (80.0%) became pregnant with an insemination index of 3.1. The highest (100.0%) fertility of cows was achieved with “Mitrec” with the best insemination index of 1.8. “Mitrec” showed the best clinical recovery of cows from chronic purulent-catarrhal endometritis.