ORAL DISSOLVING FILMS OF CHLORPHENIRAMINE MALEATE
AbstractIn this present study, we investigated phytochemical constituents screening and In-vitro antioxidant activity of hydro-alcoholic (methanol 70%v/v) extracts of Soymida febrifuga bark. Soymida febrifuga is a huge tree bearing deciduous foliage and having a tough bark belonging to the family Meliaceae. Traditionally the different parts of plant such as root, leaves, bark, and flower are used for various human ailments. Thebark extracts are used in treatment of rheumatoid arthritis asthma and good for ulcers .The decoction of the bark has bitter resin used in vaginal infections, rheumatic pains , stomach pains, wounds, dental diseases, uterine bleeding and haemorrhage .The bark is also used as an acrid, refrigerant, laxative, good for sore throat, removes ‘vata’ and cures ‘tridosha’ in Ayurveda. Apart from many uses various active constituents like methyl angolensate, luteolin 7-O-glucoside, quercetin, sitosterol, myrecetin were isolated. It also possesses various pharmacological activities such as anticancer, antihelmenthic, antioxidant ant malarial and antimicrobial. In view of this the hydro alcoholic bark extract of S. febrifuga produced a dose dependent inhibition of free radical generation of superoxide anion, hydroxyl radical and DPPH radical In vitro antioxidant activity.
Article Information
32
1859-1873
1219KB
3776
English
IJPSR
N. Prudvi Kanth*, G. Prasad and B. Vijay Kumar
Department of Pharmaceutics, Jangaon Institute of Pharmaceutical Sciences, Jangaon, Andhra Pradesh, India
prudhvi.namini@gmail.com
03 December, 2013
20 January, 2014
09 March, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.5(5).1859-73
01, May 2014