PHARMACOVIGILANCE OF HERBAL DRUGS IN POLY ARTHRITIC PATIENTS

AUS – Ayurveda, Unani and Siddha is the traditional system of medicines in India more than 3000 years old and still practiced extensively in India and neighbouring countries. Assurance of the safety margin, potency of medicinal plants that make the herbal products has now become a key issue in industrialized with developed countries. Pharmacological studies is a science relating to the screening, assessment, interaction and prevention of adverse effects particularly long term and short term side effect of medicines. The present work was carried out at National Institute of Siddha, Sanatorium, Tambaram, Chennai, and Tamil Nadu. By keeping this idea the present vigilance on Siddha formulation was conducted in poly arthritic patients. In the clinical study totally 50 arthritic patients are included in which 25 male and 25 female patients. These patients were prescribed with Cap. RGM, Tab. KVC, Tab. KUKIL and PAIN BALM. The Siddha formulation which is prescribed for the treatment was found to be 60% of efficacious which is directly observed from the patient’s feedback form. In contrast, 16% of male, 12% of female patients are not responded with the formulation. However the efficacy has to be properly determined in terms of pharmacokinetic and pharmacodynamic parameters in patient’s plasma.