PHYTOCHEMICAL ANALYSIS AND IN-VITRO ASSESSMENT OF ANTI-INFLAMMATORY ACTIVITY OF DENDROCNIDE SINUATA (BLUME) LEAF EXTRACT
AbstractDendrocnide sinuate (Blume) has been widely used in the treatment of various diseases. The plant Dendrocnide sinuate (Blume) belonging to the family Urticaceae. Many indigenous peoples used this herb to treat swelling, fever, and urinary disorders. The karbis tribes also used it as a hypersensitivity therapy. The Bodo people of Assam gather the flowers of Dendrocnide sinuata (blume) and use them as a portion of food with fish. The plant extract was subjected to a preliminary phytochemical analysis, which revealed the presence of carbohydrate, tannin, flavanoid, phenol, terpenoids, cardiac glycoside, alkaloid. As part of the investigation on the mechanism of the anti-inflammation activity, plant extract’s ability to stabilize human red blood cells membrane was studied. It was effective in the stabilization of the human red blood cells membrane. Maximum stabilization of 65.03% was observed at 150µg/ml. Diclofenac, a standard anti-inflammation drug, showed a maximum stabilization of 54.08% at 150 µg/ml concentration compared with control.
Article Information
54
4124-4127
488 KB
326
English
IJPSR
Rituparna Borah, Koushik Nandan Dutta *, Lakshyajeet Nath, Parinita Borah and Mangala Lahkar
NETES Institute of Pharmaceutical Science, NEMCARE Group of Institution, Guwahati, Assam, India.
koushik5dutta@gmail.com
27 December 2022
11 April 2023
30 May 2023
10.13040/IJPSR.0975-8232.14(8).4124-27
01 August 2023
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