RECENT APPROACHES IN SELF EMULSIFYING DRUG DELIVERY SYSTEM
AbstractSelf emulsifying is a topic of current interest for overcoming the formulation difficulties of drugs with poor aqueous solubility. SEDDS are isotropic mixture of oil, surfactant and co-surfactant with a unique ability to form fine oil-in-water (o/w) emulsions or micro emulsions upon mild agitation in the gastrointestinal tract which present the drug in a solubilized form, and the small size of formed droplet provides a large interfacial surface area for drug absorption. It is a promising strategy to improve the rate and extent of oral absorption. The SEDDS were characterized for robustness to dilution, globule size, polydispersity index and zeta potential.
Article Information
18
4192-4201
596KB
1497
English
Ijpsr
Khushboo Singh*, Monika Sharma, Kamal Gandhi and Asha
Ram Gopal College of Pharmacy, Sultanpur, Tehsil-Farrukhnagar, Distt. Gurgaon, 122001, Haryana, India
khushboosingh04@gmail.com
29 May, 2012
14 October, 2012
29 October, 2012
http://dx.doi.org/10.13040/IJPSR.0975-8232.3(11).4192-01
01 November,2012
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