REPLACEMENT OF ORGANIC SOLVENTS WITH ENVIRONMENTAL ECO-FRIENDLY SOLVENTS FOR RP-HPLC ANALYSIS
AbstractBackground: Solvents are major part in chemical industry. Solvents have major impact on cost as well as safety and health issues. Many more organic solvents are considered toxic. Thus the concept of green chemistry is introduced which eliminate or reduce the use of hazardous solvents/chemicals from analytical process for the eco-friendly environment and health without any compromise in Analytical performance. Aim: Thus, the green chemistry goals to eliminate the use of hazardous chemicals and to search the non-hazardous solvents. Some of the methods are identified that are eco-friendly which replace the use of harmful organic solvents by use of alternatives such as The EHS method, bio-solvents, solvent less preparation techniques, RP-HPLC and UP-HPLC, Micellar liquid chromatography, Eco-friendly and economic analytical methods using hydrotropic solubilization. Result and Discussion: From the results it is identified that Contamination prevention, whether through green chemistry or other means, will be challenging for the environmental pollution.
Article Information
17
172-186
1066 KB
399
English
IJPSR
Fatema M. Bardanwala * and Megha Shah
Department of Pharmaceutical Quality Assurance, Laxminarayan Dev College of Pharmacy, Bholav, Bharuch, Gujarat, India.
bardanwalafatema1999@gmail.com
13 April 2022
14 July 2022
19 July 2022
10.13040/IJPSR.0975-8232.14(1).172-86
01 January 2023
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