ROLE OF MEDICINAL HERBS IN CISPLATIN-INDUCED TOXICITY: AN OVERVIEW
AbstractCisplatin is a widely used chemotherapeutic agent. It is highly effective against various malignancies but is often limited by its severe toxic effects, including nephrotoxicity, hepatotoxicity, neurotoxicity, and ototoxicity. Oxidative stress, inflammation, and apoptosis are key mechanisms underlying cisplatin-induced organ damage. In recent years, medicinal herbs have gained attention as potential protective agents due to their antioxidant, anti-inflammatory, and cytoprotective properties. These investigations will contribute to a deeper understanding of how these herbal treatments can effectively interact at the molecular level, potentially improving therapeutic outcomes for patients suffering from the adverse effects of cisplatin on kidney function.
Article Information
10
3273-3284
695 KB
2
English
IJPSR
Iffat Fatma Siddiqui, Sony Chauhan, Avinash Kumar and Sanjay Kumar *
Department of Pharmacology, Hygia Institute of Pharmacy, Lucknow, Uttar Pradesh, India.
sanjaykumar.niec@gmail.com
22 May 2025
11 November 2025
24 November 2025
10.13040/IJPSR.0975-8232.16(12).3273-84
01 December 2025
Download