ROUTINE BLEEDING TECHNIQUES IN LABORATORY RODENTSAbstract
Collecting blood from Lab animals is necessary for a wide variety of scientific studies, and there are a number of efficient methods available. It is important to remember that blood collection can stress the animals, and may have an impact on the outcome of research data. Potential adverse affects viz. Hypovolemic shock, anemia, stress, haemorrhage, bruising, thrombosis; infection at the site of needle entry, phlebitis, scarring, and nerve damage should be avoided. It is essential to be able to recognize the clinical signs of shock and to take appropriate action. The purpose of this article is to review the different methods of blood collection, their advantages, limitations, monitoring, restraints, possible adverse effects, their prevention and control in laboratory rodents.
Madhuri Oruganti* and Sudesh Gaidhani
Central Council for Research in Ayurvedic Sciences, Dept. of AYUSH, Ministry of Health & Family Welfare, Janakpuri, New Delhi, India
24 November, 2010
27 January, 2011
17 February, 2011
01 March, 2011