SALVIA GENUS AND TRITERPENOIDS

SALVIA GENUS AND TRITERPENOIDS

Shyamal K. Jash ¹, Dilip Gorai ² and Rajiv Roy ^*3

Department of Chemistry ¹, Saldiha College, Saldiha, Bankura - 722173, West Bengal, India.

Department of Chemistry ², Bolpur College, Bolpur, Birbhum - 731204, West Bengal, India.

Independent Researcher ³, Bhatgonna (Dignagar), Burdwan - 713128, West Bengal, India.

ABSTRACT: Salvia L., is one of the largest genera from Lamiaceae (Labiatae) family which comprises 900 species and is widely distributed in various regions of the world like in America, Europe, Asia. In this review article, the triterpenoid constituents were investigated from all of the Salvia plants to date are reported. About 214 triterpenoids of different classes were isolated and characterized from 113 species of salvia genus. So far the Salvia plants were investigated for their diterpenoids, phenolics and monoterpenes (volatile oils), especially for diterpenoids rather than for their triterpenoid constituents. However, during the isolation procedures of Salvia plant extracts, ursolic and oleanolic acids are common triterpenoid with other constituents isolated. Salvia, in Latin named “salvare”, which means “to heal” so by name its medicinal importance was understand, since from ancient times different salvia species were used to  cure more than sixty different ailments ranging from aches to epilepsy, and mainly to treat colds, bronchitis, tuberculosis, hemorrhage, and menstrual disorders. Salvia L., is one of the largest genera from Lamiaceae (Labiatae) family which comprises 900 species and is widely distributed in various regions of the world like in America, Europe, Asia.

INTRODUCTION: Salvia L., is one of the largest genera from Lamiaceae (Labiatae) family which comprises 900 species and is widely distributed in various regions of the world like in America, Europe, Asia. The plants are typically 30-150 cm tall, herbaceous or suffruticose, and perennial, rarely biennial, or annual, with attractive flowers in various colors.

Salvia, in Latin named “salvare”, which means “to heal” so by name its medicinal importance was understand, since from ancient times different salvia species were used to  cure more than sixty different ailments ranging from aches to epilepsy, and mainly to treat colds, bronchitis, tuberculosis, hemorrhage, and menstrual disorders.

In this review article, the triterpenoid constituents were investigated from all of the Salvia plants to date are reported. About 214 triterpenoids of different classes were isolated and characterized from 113 species of salvia genus. So far the Salvia plants were investigated for their diterpenoids, phenolics and monoterpenes (volatile oils), especially for diterpenoids rather than for their triterpenoid constituents. However, during the isolation procedures of Salvia plant extracts, ursolic and oleanolic acids are common triterpenoid with other constituents isolated. This review is an effort to attract natural product chemist to give their contribution on isolation of triterpenoid’s from Salvia genus ^1-158.

MATERIALS AND METHODS:

The triterpenoids isolated and identified from Salvia genus, were searched across the Medline (National Library of Medicine) and Science Direct databases, Pubmed, ACS, Pols-one, Wiley chem. abstract, Springer link, RSC, Google and Google Scholar. The data were updated in June 2016, using the search terms Salvia triterpenoid, triterpenoid from Salvia genus, triterpenoid, phytochemical, chemical constituents, from Salvia as keywords. In addition, the reference lists of all papers identified were thoroughly reviewed.

RESULTS AND DISCUSSION:

List of triterpenoid(s) & their Structure(s) from salvia species: This review article compiled almost 214 triterpenoids from 113 species of salvia which are listed in Table 1 and Table 2, with their structure in Fig.1.

TABLE 1: LIST OF TRITERPENOIDS

TABLE 2: LIST OF SALVIA SPECIES FROM WHICH TRITERPENOID(S) WERE ISOLATED

Structure(s):

FIG.1: URSANE TRITERPENOIDS

FIG. 2: OLEAN TRITERPENOIDS

FIG. 3: LUPANE TRITERPENOIDS

FIG.4: DAMMARANE TRITERPENOIDS

FIG.5: MISCELLANEOUS TRITERPENOIDS

CONCLUSIONS: The present review deals with up to date literature on triterpenoid isolated from Salvia genus regarding exhibited by the plant extracts. We are quite optimistic that this review article will surely stimulate present day researcher to undertake more systematic research work on this important genus for isolation of triterpenoids.

COMPETING INTERESTS: The authors declare no conflict of interest.

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     How to cite this article:

     Jash SK, Gorai D and Roy R: Salvia Genus and Triterpenoids. Int J Pharm Sci Res 2016; 7(12): 4710-32.doi: 10.13040/IJPSR.0975-8232.7(12).4710-32.

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