SCREENING OF MEDICINAL PLANTS USED FOR PREVENTION AND TREATMENT NEURODEGENERATIVE DISEASES: A REVIEW

Amyotrophic lateral sclerosis (ALS), Parkinson’s disease, Alzheimer’s disease, and Huntington’s disease occur as a result of the neurodegeneration process. No specific treatment was found to reduce or stop neurodegenerative diseases. In conventional medicine, many plants have been used to treat neurodegenerative diseases. Natural products play an important role in the prevention and treatment of various neurodegenerative diseases, as well as neuronal dysfunction. Different studies suggest that natural products, such as polyphenolic and plant-separated alkaloids, may delay neurodegeneration and improve memory and cognitive function. Ethnopharmacological studies have provided data to identify potential new drugs in plant sources. Recently many drugs found in medicines have been isolated from plants or their origin, including anticholinesterase (Anti-ChE) isolated plant alkaloids that have been investigated in terms of their potential in the treatment of Alzheimer’s disease (AD). The anti-inflammatory and antioxidant activities of plants and soluble components of plants are used to improve inflammation, anxiety, seizures, and more. Medicinal plants have beneficial properties due to the presence of complex chemical compounds to treat toxins in the nervous system. This review article explored the use of medicinal plants to treat neurodegenerative diseases.