STATISTICAL ANALYSIS ON EFFECT OF SITAGLIPTIN AND GLIMEPIRIDE ON PANCREATIC BETA-CELLS DURING THE TREATMENT OF TYPE-2 DIABETIC MELLITUS
AbstractThe study aimed to analyze the treatment of Sitagliptin with Glimepiride to improve pancreatic beta-cells in T2DM patients. Beta cells are a type of cell found in the pancreatic islet and also synthesize, secrete insulin and amylin. Sitagliptin is found to be maintaining the beta-cells function and glycemic control in T2DM patients. Randomly diabetes mellitus type-2 (T2DM) patients’ data is collected (110 patients) for statistical analysis. For this study, T2DM patients enrolled with the age of 30-60 years, treated with Sitagliptin and Glimepiride once a day. The baseline of HbA1c >7.0% to <10.5%; thus, the performed student t-test is to find out the significant role. The 110 patients are distributed into two groups: one Sitagliptin user group (n=62) and the second Glimepiride user group (n=43). The sitagliptin treatments may also protect also beta cells as the pancreas may not able to regenerate beta-cell.
Article Information
45
4993-4998
572 KB
863
English
IJPSR
Praveen Yadav, Bhaskar Joshi and A. Geetha Bhavani *
Department of Chemistry, Noida International University Research Innovation Centre, Noida International University, Gautama Buddha Nagar, Greater Noida, Uttar Pradesh, India.
ageethabhavani@gmail.com
01 October 2020
09 February 2021
23 June 2021
10.13040/IJPSR.0975-8232.12(9).4993-98
01 September 2021
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