STUDY ON SAFETY AND EFFICACY OF DIFFERENT MODALITIES IN THE POST-OPERATIVE PAIN MANAGEMENT IN A TERTIARY CARE TEACHING HOSPITALAbstract
ABSTRACT: Background: Postoperative pain control is an important part of effective postoperative care. However, 30 – 80% of postoperative patients complain about moderate to severe post-surgical pain as a result of the surgical procedure or a pre-existing disease. Aim: To assess the safety and efficacy of different modalities of postoperative pain management in post surgical wards of a tertiary care hospital. Method: It’s a prospective study was conducted in 213 patients of either gender, aged between 18 – 65 years. Patients were followed up from surgery till discharge or till the 4th postoperative day, the drugs given for pain relief both as single drug and combination drugs and adverse effects were monitored. The severity of pain was assessed using a numeric pain rating scale after 1 h of surgery, then followed by 2 h, 4 h, 6 h, 12 h, 24 h, 48 h and 96 h. Patient satisfaction with the analgesic therapy given was recorded at the time of discharge or after 4th postoperative day using 5 point Likert’s Scale. The data collected were tabulated and analyzed statistically using SPSS.16 software. Results: On comparing the various modalities of pain management, the combination therapy was found to be more effective than the single drug modality, as significant reduction in pain score was seen at 6th, 12th, 24th and 48th h with a p-value < 0.05. Conclusion: All the modalities used for postoperative pain management were safe and effective. The multimodal analgesic therapy for postoperative pain was more effective than the single modal analgesic therapy.
P. Thennarasu *, N. V. Rani, G. Ragesh and G. Vidhya
Department of Pharmacy Practice, Faculty of Pharmacy, Sri Ramachandra Medical College and Research Institute (Deemed to be University), Porur, Chennai, Tamil Nadu, India.
19 October, 2017
24 February, 2018
18 March, 2018
01 July, 2018