SYNERGISTIC PHARMACOLOGICAL EFFECTS OF PHYTOCHEMICALS DERIVED FROM GINGER, GARLIC AND TULSIAbstract
This review article is focused at highlighting the therapeutic values of phytochemicals derived from the natural herbs ginger, garlic and tulsi. It is shown that the phytochemicals derived from these natural herbs work synergistically and exert similar pharmacological profile. The main actions include antioxidant and anti-inflammatory properties. Recommendations are made to follow the antioxidant status at the molecular level. A dietary supplement containing a mixture of 6-gingerol, 6-shogaol, 6-paradol, allicin, ajoene, eugenol and eucalyptol is highly recommended for the ageing patients. There is scope for deriving a common pharmacophore leading to the development of a good anti-inflammatory molecule with reduced side effects which may be beneficial for the elderly with multiple disorders. Information regarding the pharmacological effects and various targets of these phytochemicals has been compiled in the form of tables to provide easy reference for future studies.
Prakhar Shukla , Sweta Sharma, Arpita Yadav * and Veejendra K. Yadav
University Institute of Engineering and Technology, Chhatrapati Shahu Ji Maharaj University, Kanpur, Uttar Pradesh, India
14 June, 2015
16 July, 2015
29 September, 2015
01 December, 2015