SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 3-(2′-HYDROXY-3′-NITRO-5′-METHYLPHENYL)-5-(ARYL/HETERYL) PYRAZOLES
AbstractHeterocyclic compounds are well known for their different biological activities like anti-inflammatory, antibacterial, antifungal, anticancer, insecticidal, pecticidal, antibiotic, etc. the versatile applications of oxygen, nitrogen and sulphur containing heterocyclic compounds have made this area of extensive research. The present study deals with the synthesis of some new 3-(2′-hydroxy-3′-nitro-5′-methylphenyl)-5-(aryl/heteryl) pyrazoles synthesis from 1-(2′-hydroxy-3′-nitro-5′-methylphenyl) – 3 – aryl/heteryl – 2-propen-ones i.e. chalcone by reaction with hydrazine hydrate in ethanol and synthesized compounds screening for antimicrobial activity
Article Information
50
2663-66
402
1218
English
IJPSR
S. B. Borul * and S. V. Agarkar
Department of Chemistry , Late Ku. Durga K. Banmeru Science College, Lonar, M.S. India
sbb_06@rediffmail.com
06 December, 2015
16 January, 2016
03 April, 2016
10.13040/IJPSR.0975-8232.7(5).2663-66
01 June 2016