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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

IJPSR is indexed with Embase

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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SYNTHESIS OF PHENYL HYDRAZINE SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AND THEIR BIOLOGICAL ACTIVITY

Abstract

Condensation of o-phenylene diamine with chloro acetic acid gave 2-chloromethyl benzimdazole, which undergoes halide replacement with phenylhydrazines to give the corresponding NN’ disubstituted hydrazines. The synthesized compounds were subjected to microbiological screening and In- vitro anti-inflammatory activity.

 

Article Information

6

34-38

382 KB

2067

13

English

IJPSR

VENKATARAMANA HS C., SINGH A., TIWARI A.*, TIWARI V.

Department of Pharmaceutical Chemistry, M. S. Ramaiah College of Pharmacy*, Bangalore, Karnataka, India

abhishekt1983@gmail.com

14 December, 2009

23 December, 2009

29 December, 2009

http://dx.doi.org/10.13040/IJPSR.0975-8232.1(1).34-38

01 January, 2010

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