TECOMELLA UNDULATA (SM.) SEEM.- GC-MS ANALYSIS OF FLAVONOIDS AND INHIBITORY ACTIVITY AGAINST PATHOGENIC MICROBES

Tecomella undulata (Sm.) seem is a monotypic genus belonging to family Bignoniaceae. The plant holds the tremendous potential of medicinal value and has been traditionally used in various ailments like syphilis, leukoderma, blood disorders, to name a few. The plant has gained prominence due to the presence of some prominent secondary metabolites. The present study focuses on the GC-MS analysis of extracts of all the plant parts of T. undulata, which revealed the presence of certain bioactive compounds like Quericitin, Kaempferol, stigmasterol, sitosterol, thiazoline, phytol, pthalic acid, methyl alpha ketopalmitate and so forth. A total of about 20 bioactive compounds were identified. The antimicrobial activity of the extracts was assayed against pathogenic bacteria and fungi. The flavonoids from leaf extracts showed highest antimicrobial activity against C. albicans, S. aureus, E. coli, and B. subtilis. This also correlates with the highest amount of Flavonoids present in leaves followed by the amount present in roots. The study thus infers that the presence of bioactive components may be the principle behind the antimicrobial property of different plant parts, and therefore Tecomella forms a potential plant for herbal drug formulation.