THE ROLE POLYMERIC NANOPARTICLES IN CANCER CHEMOTHERAPY: A NARRATIVE SYNTHESIS OF THE EVIDENCE
AbstractChemotherapy is a familiar treatment technique that uses chemical drugs to kill cancer cells. This technique affects normal healthy tissues because it is unspecific and has toxic side effects. Now a days, nano technology application in chemotherapy have helped to solve uncontrolled problems of drug delivery and other side effects. Nanoparticles (NPs) can provide outstanding advantages over conventional drug delivery by having excellent properties such as controlled mode of action, different methods administration, and the ability to transport organic and inorganic molecules. Special ligands attached to polymeric NPs target the tumour site because of their chemical affinity to the malignant tissues. This article reviews the characterization, fabrication and application of NPs used in cancer chemotherapy. Moreover, different forms of polymeric chemotherapy was explored and analysed to better understand the effects of nano particles on cancer chemotherapy.
Article Information
9
2263-2272
768 KB
117
English
IJPSR
Vothani Sarath Babu, Enamala Jeevana Jyothi, C. Dharani and S. Pavithra
Department of Pharmaceutics, S.V.U College of Pharmaceutical Sciences, Sri Venkateswara University, Tirupati, Andra Pradesh, India.
sarathvothani@gmail.com
13 February 2024
07 May 2024
19 April 2024
10.13040/IJPSR.0975-8232.15(8).2263-72
01 August 2024
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